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A spermatocyte needs to split into four cells, while an oocyte needs to split into only one because many sperm are needed to fertilize a single egg. The mitotic spindle starts to form, the chromosomes start to condense, and the nucleolus disappears. The absence of securin allows another enzyme called separase to act on cohesin molecules holding the two chromatids together. During which of the following processes do homologous pairs of chromosomes align adjacent to one another at the metaphase plate of a cell? main term: ___________. Prophase: Sister chromatids are condensed, centrosome separates, microtubules form between centrosomes (poles) to make mitotic spindle Prometaphase: Nuclear envelope breaks down; spindle can . If you're behind a web filter, please make sure that the domains *.kastatic.org and *.kasandbox.org are unblocked. During mitosis, when do sister chromatids separate? During mitosis, DNA condenses to form visible chromosomes, and these two identical copies, or sister chromatids, are attached to each other and form an X shape. During mitosis, the two sister chromatids that make up each chromosome separate from each other and move to opposite poles of the cell. 2. Anaphase - Definition and Stages in Mitosis and Meiosis 2. alignment of chromosomes at the equator This was initially discovered as Sister Chromatid Exchange (SCE) and later was found to be even more effective at DNA repair than methods using the homologous pair. When a protein is tagged with a chain of ubiquitin molecules, it is seen as a signal for the protein to be degraded by the proteasome. 5, A diploid organism whose somatic (nonsex) cells each contain 32 chromosomes produces gametes containing _____ chromosomes. The single DNA molecule in the chromosome must be replicated. 2. Direct link to mario.medrano92889's post Is actin in cytokineses a, Posted 8 years ago. Which of the following answers describes the phenomenon of crossing over in meiosis? Centromeres of sister chromatids disjoin and chromatids separate.