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Malignancies can present as autoimmune diseases or they can mimic flare of Rheumatological diseases. Studies find ANA positivity common, even in healthy people De Vlam and colleagues3 studied 485 healthy volunteer blood donors and found that 20% of the women and 7% of the men had a positive ANA result. I'd first rather get more general information about the ANA. Epub 2021 Dec 7. Sometimes, it is difficult to ascertain whether autoimmune disorders have caused cancers or malignancies have caused autoimmune disturbances. The pattern refers to the distribution of staining produced by autoantibodies reacting with antigens in the cells. However, it is essential to remember that a positive ANA test does not mean you have Lupus. Elevated ANA is sometimes found in healthy individuals, and has been consistently associated with female sex and older age (12-14). This decision guide is designed for persons with a positive antinuclear antibody (ANA) who would like to find out more about this test and what the test result may mean. What to expect during an ANA test - Medical News Today 01). The following is a list of common rheumatic and non-rheumatic conditions that are related to positive Antinuclear antibodies (ANA). Other blood work is fine? Alserawan L, Anguera G, Zamora Atenza C, Serra Lpez J, Martnez-Martnez L, Riudavets Meli M, Sullivan I, Barba Joaquin A, Majem Tarruella M, Vidal S. Int J Mol Sci. Lupus When the test is positive it highly shows that one is suffering from an autoimmune condition like lupus. Drug-Induced Autoimmune Diseases - Pharmacy Times HHS Vulnerability Disclosure, Help After all, cancer can develop in any organ, including the brain. A study of nearly 100,000 Swedish prostate-cancer patients presented at a 2008 meeting of the American Society of Clinical Oncology found a 12% reduced risk of death among men with RA compared to . And if the ANA test is positive, your blood can be tested for the presence of particular antinuclear antibodies, some of which are specific to certain diseases.