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Also, discovering multiple food allergies and medication allergies and sensitivities. 2020 Mar;52(2):51-61. doi: 10.23822/EurAnnACI.1764-1489.133, 3. doi: 10.1093/nar/gnf056. Urologists commonly treat urinary tract infections, kidney stones, bladder control problems, prostate problems, and cancer. Mayo Clinic is a nonprofit organization and proceeds from Web advertising help support our mission. History of a physician-diagnosed mast cell disorder (e.g., mastocytosis, mast cell activation syndrome, or hereditary alpha-tryptasemia). Using the American Psychiatric Association tool you may need to expand your mile radius or search by state. Examining clinical and factors that impact response to antiTNF from www.mayoclinic.org. Surgeons can also perform operations that help doctors learn more about a condition.Find a surgeonin your area (directory by the American College of Surgeons). Urologists also manage conditions affecting the reproductive system of males. They can manage blood vessel disorders using diet, exercise, medication, and surgery.Please consult your primary care doctor for help finding a vascular medicine specialist. Hereditary alpha tryptasemia (HAT) This is an inherited disorder that causes high levels of tryptase, an enzyme released by mast cells along with histamine. Clinical procedures may include a range of different tests depending on your body system being evaluated. Several features that may be shared among those who have hereditary alpha tryptasemia syndrome are multiple symptoms affecting a variety of systems including (but not limited to) these: Chronic skin flushing, itching, or hives Bee sting allergy September 13, 2021. Until then we cannot be completely sure which symptomswhether or not they are on the list above-- can be directly attributed to having hereditary alpha tryptasemia. Maxillofacial surgeons may operate to reduce pain, repair injuries, improve appearance, and restore or improve function.Find a maxillofacial surgeon in your area (directory by the American Association of Oral and Maxillofacial Surgeons). While large studies of multiple different ethnicities need to be done, the estimate is that hereditary alpha tryptasemia may be present in a similar percentage of the general population. Future research will be dedicated to identifying symptoms and populations commonly associated with hereditary alpha tryptasemia and finding a treatment that specifically targets alpha tryptase and its mechanisms of action to better advise and manage those who carry multiple alpha genes. Additional testing and referrals may be needed to make a firm diagnosis. It is not clear the extent to which activated mast cells contribute to this disease, nor whether mast cell activation plays any role in symptoms.