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I got the index where SampleID.A == SampleID.B && ParentID.A == ParentID.B. How to remove rows from a dataframe that are identical to another To manipulate dates in pandas, we use the pd.to_datetime () function in pandas to convert different date representations to datetime64 . In this article, Lets discuss how to check if a given value exists in the dataframe or not.Method 1 : Use in operator to check if an element exists in dataframe. Let's check for the value 10: Is it plausible for constructed languages to be used to affect thought and control or mold people towards desired outcomes? tensorflow 340 Questions scikit-learn 192 Questions Determine if Value Exists in pandas DataFrame in Python | Check & Test any() does a logical OR operation on a row or column of a DataFrame and returns . Another method as you've found is to use isin which will produce NaN rows which you can drop: In [138]: df1[~df1.isin(df2)].dropna() Out[138]: col1 col2 3 4 13 4 5 14 However if df2 does not start rows in the same manner then this won't work: df2 = pd.DataFrame(data = {'col1' : [2, 3,4], 'col2' : [11, 12,13]}) will produce the entire df: If the element is present in the specified values, the returned DataFrame contains True, else it shows False. In this case data can be used from two different DataFrames. You then use this to restrict to what you want. a bit late, but it might be worth checking the "indicator" parameter of pd.merge. index.difference only works for unique index based comparisons. Since 0.17.0 there is a new indicator param you can pass to merge which will tell you whether the rows are only present in left, right or both: So you can now filter the merged df by selecting only 'left_only' rows. 1 I would recommend "pivoting" the first dataframe, then filtering for the IDs you actually care about. list 691 Questions This method returns the DataFrame of booleans. Browse other questions tagged, Where developers & technologists share private knowledge with coworkers, Reach developers & technologists worldwide. It would work without them as well. function 162 Questions @BowenLiu it negates the expression, basically it says select all that are NOT IN instead of IN. pandas dataframe-python check if string exists in another column tkinter 333 Questions This article discusses that in detail. You get a dataframe containing only those rows where col1 isn't appearent in both dataframes.