In the Synaptic Cleft, there are neurotransmitters that are diffusing from one neuron to the next neuron, and then undergoing receptor-mediated endocytosis with the receptors in the "receiving" neuron (which should require space for receiving them). Once a nerve impulse has triggered the release of neurotransmitters, these chemical messengers cross the tiny synaptic gap and are taken up by receptors on the surface of the next cell. Functionally, the nervous system can be divided into those regions that are responsible for sensation, those that are responsible for integration, and those that are responsible for generating responses. I do not know what :transactions_ you are speaking of, but I found this. It is definitely broken down after it enters the postsynaptic neuron, right? The mechanism of synapse transmission can be divided into the presynaptic and postsynaptic mechanisms. Neurotransmitter Action: Ionotropic Receptors, 12. IPSPs have the opposite effect. The name for that specific structure depends on its location. On the other hand, if an IPSP occurred together with the two EPSPs, it might prevent the membrane potential from reaching threshold and keep the neuron from firing an action potential. $$. 2011;91(2):555-602.doi:10.1152/physrev.00048.2009. Sensation starts with the activation of a sensory ending, such as the thermoreceptor in the skin sensing the temperature of the water. Neurons are polarized cells, based on the flow of electrical signals along their membrane. The sensations that lead to autonomic functions can be the same sensations that are part of initiating somatic responses. Action potential arrives at presynaptic axon terminal and depolarizers the presynaptic membrane. The temperature information represented in that electrical signal is passed to the next neuron by a chemical signal that diffuses across the small gap of the synapse and initiates a new electrical signal in the target cell. The area of the postsynaptic membrane modified for synaptic transmission is called the postsynaptic density. A synaptic connection between a neuron and a muscle cell is called a neuromuscular junction. These dendrites then receive chemical signals from other neurons, which are then converted into electrical impulses that are transmitted toward the cell body. Image credit: based on similar image in Pereda. Schematic of synaptic transmission. The soma and the nucleus do not play an active role in the transmission of the neural signal. Direct link to Ivana - Science trainee's post EPSPs are graded potentia, Posted 3 years ago. These tiny protrusions receive information from other neurons and transmit electrical stimulation to the soma.